This book “minimally invasive spinal surgery: principles and evidence-based practice” thoroughly reviews the preclinical and clinical data on minimally invasive spinal surgery and describes and illustrates the current effective techniques. Minimally invasive spine surgery (MISS) is a type of surgery on the bones of your spine (backbone). This type of surgery uses smaller incisions than standard surgery. This book comprised of 4 sections that focus on cervical spine, thoracic spine, lumbar spine, and cost effectiveness and advanced technologies, which are further divided into 32 chapters. The book focuses on the application of specific, state-of-the art technologies as well as on the use of biomaterials in reconstructive procedures of the spine. Individual chapters describe not just the clinical indications and surgical techniques associated with each procedure, but also evaluate clinical outcomes and standards in analytical methodology and quality control. ...